Prof. Vered Padler-Karavani Lab

Our lab is studying the mechanisms that govern glycan immune recognition and responses in animal models and humans, both in vitro and in vivo. 

 

We combine glycobiology, immunology, biotechnology, bioinformatics, xenotransplantation and cancer research, and use cutting edge technologies within these disciplines, including glycan microarray, glyco-nanotechnology, CAR-T immunotherapy and AI-based bioinformatics. 

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Current interests include:  Immunological mechanisms of unique anti-glycan antibodies; Anti-carbohydrate antibodies in mucosal secretions and sera; Diet and microbiome effects on anti-glycan antibodies and disease risk; Glycoimmunology in xenotransplantation, as members of the EU TRANSLINK consortium; Development novel diagnostics and therapeutics to chronic inflammation mediated diseases, such as cancer, autoimmunity and allergy; Development of bio-nanotechnology tools based on glycan recognition; Improving drug biotherapeutics by glycoengineering.